Group Leader, Research Products – Cambridge Isotope Laboratories, Inc. – Andover, MA

Cambridge Isotope Laboratories has an exciting opportunity as we seek a Group Leader for our Research Products team in our Andover, MA location. As the leading company in a niche scientific market, CIL works with cutting edge researchers in clinical diagnostics, metabolic research, proteomics, environmental testing, protein discovery, drug development, metabolomics, and industrial research. CIL’s growing customer base spans academia, pharmaceutical and industry, enabling collaborations with Nobel laureates, industry-leading scientists, and chemists. CIL partners with leading instrument manufacturers as well pioneering research groups that have expertise in product development and drive market growth. CIL is a subsidiary of the Otsuka Pharmaceutical Group and has had consistent growth for 40 years.

The Group Leader is responsible for overseeing a team (typically 4 – 7) of BS/MS and PhD level Chemists performing the de novo synthesis of a wide variety of isotopically labeled targets to customer and production requirements. Managerial responsibilities include: being a safety leader, understanding safety policies, ensuring the implementation of safety policies, work supervision and evaluation, performance development, driving continuous improvement projects and addressing employee relations issues. Additionally, the Group Leader is responsible for carrying out complex, non-routine synthetic chemistry.


  • Ensure the implementation of CIL safety policies and other policies in general
  • Review and evaluate safety aspects of the projects to ensure safety standards are met, as well as having the awareness to recognize potential instances of abuse
  • Lead by example to ensure team members maintaining good housekeeping of their area by using 5S
  • Committed to driving continuous improvement projects
  • Oversee and direct their team members in the process and completion of synthetic chemistry set forth in the project system
  • Utilize advanced knowledge of theoretical and practical aspects of synthetic chemistry to carry out complex synthetic procedures and solve technical problems
  • Mentor and coach group members to foster and enhance professional and technical development within the department
  • Conduct team member performance evaluations annually
  • Develop effective relationships with external departments (e.g. Materials Control, Quality Control, and Technical Services)
  • Keep an accurate and detailed laboratory notebook
  • Synthesize complex, non-routine target compounds generally containing 15N, 18O, D and/or 13C
  • Analyze and interpret data obtained from nuclear magnetic resonance (NMR), ultraviolet (UV), mass (MS), HPLC and infrared (IR) spectroscopy
  • Utilize purification techniques which include: chromatography, distillation, recrystallization and sublimation
  • Perform any related work as necessary


  • Ph.D. in Synthetic Organic Chemistry or closely related field
  • Five (5) years of work experience in organic chemistry and/or synthesis including two years managing other chemists and a variety of ongoing synthetic chemistry projects
  • Excellent laboratory technique and communication skills, a broad knowledge of organic synthetic methods, strong analytical skills and a proficiency in chemical separation and identification of organic compounds
  • Working experiences in fluorine chemistry is a plus
  • Regularly performs bench chemistry which requires standing, bending and stooping
  • Must be able to lift 50 lbs. daily, transport drums of chemicals using a drum dolly, some drums up to 55 gallons


CIL offers a competitive salary and a comprehensive benefit program including generous paid time off, health insurance with 100% company paid deductibles, Long Term Incentives and 6% matching 401K plan.

CIL is an EEO/Affirmative Action employer.

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About us:

Cambridge Isotope Laboratories, Inc. (CIL) is the world’s leading producer of stable isotopes and stable isotope-labeled compounds. With nearly 600 employees and laboratories in four countries, CIL specializes in the process of labeling biochemical and organic compounds with highly enriched, stable (nonradioactive) isotopes of carbon, hydrogen, nitrogen and oxygen. Our chemists substitute common atoms (e.g., 1H, 12C, 14N, 16O) with rare, highly valued isotopes (e.g., 2H or D, 13C, 15N, 18O) so that the final product can be readily measured or traced using mass spectrometry (MS) or nuclear magnetic resonance (NMR). CIL’s products are utilized in laboratories, medical, government and academic research centers and health care facilities worldwide.

We are proud that CIL products have contributed to medical advancements in cancer research, new-drug development, environmental analysis, and medical diagnostic research. In the past decade, as the fields of proteomics and metabolomics have developed as leading techniques for determining biomarkers for disease presence, progression and the monitoring of therapeutic response, CIL has worked closely with industry leaders and researchers to provide the stable isotope-labeled tools needed for improved quantitation and qualification of complex biological systems.

After decades of research, stable isotopes have found their place in an ever expanding commercial scale applications in pharmaceuticals, semiconductors, flat panel displays as well as other high technology fields specifically with deuterium oxide (D2O) and deuterium gases. Pharmaceutical companies have begun to investigate deuteration of molecules that may provide advantages over their existing nondeuterated counterparts. In addition, increasing research into the potential medical advantages of new deuterated drugs is also occurring. In high technology, deuterated organic molecules and deuterium gas are commonly used in the manufacturing of microelectronics and OLEDs, which contribute to the increased lifetime of the devices.

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