Shrestha Auditory Physiology & Plasticity Research
The Shrestha Lab at Mass Eye and Ear/Harvard Medical School studies mechanisms that orchestrate plasticity and stability of multiple facets of neuronal identities in the mouse auditory system, using cutting-edge molecular genetic approaches such as scRNA-seq, scATAC-seq, and CRISPR/Cas9-based genomic editing.
We are looking for a Research Assistant to assist us across various projects in the laboratory. The candidate will be primarily responsible for: 1) regular handling of live mice for the purpose of setting up crosses, weaning litters, collecting tissue samples for genotyping, injecting anaesthetics and other drugs, 2) extracting, dissecting, processing and sectioning brain tissues, 3) detecting mRNA and proteins of interest by in situ hybridization and immunohistochemistry, 4) preparing buffers and reagents for molecular biology, 5) gel electrophoresis and imaging, 6) acquiring images using epifluorescence and confocal microscopy, 7) assisting in general laboratory maintenance, including setting up of equipments, and organizing reagents and supplies. Offering a broad exposure to standard techniques employed in a molecular neuroscience lab, this position is ideal for individuals seeking to pursue graduate studies in biomedical sciences or medicine.
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Bachelor’s degree with at least six months of relevant work experience required. Comfort with handling live mice and performing procedures on anesthetized mice is a must. Demonstrated abilities in relevant laboratory techniques with one or more years of experience in the stated techniques preferred. May be required to work with hazardous materials. May occasionally be required to lift, move, and transport laboratory equipment. The ideal candidate is detail-oriented, has excellent organizations skills, can multi-task efficiently, and loves to learn new concepts and techniques related to studies of the nervous system.
Mass General Brigham is an Equal Opportunity Employer & by embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law.
Work Locations MEI Mass Eye and Ear Main Building Boston 243 Charles Street Boston 02114
Organization Mass. Eye and Ear (MEE)
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