Vice President and Chief Medical Partner, Cross-Portfolio – Genentech – South San Francisco, CA

POSITION OVERVIEW:

At USMA, we focus on broadening opportunities for patient access by ensuring that health care stakeholders have the evidence they need on our products and the confidence in that evidence to make informed treatment decisions. As a key pillar in the broader Genentech organization, USMA has a pivotal role in bridging internal partner functions (including Research, Product Development, Commercial, and Government Affairs) and collaborating across the dynamic health ecosystem to ultimately deliver better patient outcomes while making care more accessible and affordable for all.

The Cross-Portfolio CMP (CP CMP) will act as the medical lead on Personalized Health Care (PHC) leading a team of direct reports and acts as a network leader and partners with senior leaders across the Genentech and Roche enterprise to ensure excellence in execution initially focussing on the Oncology PHC strategy, learning and sharing best practices, and incorporating customer insights to adapt and inform future direction.

They will develop or co-develop all cross-portfolio PHC strategies and activities for all TAs. Given that the most mature cross portfolio work is in Oncology with ongoing partnerships and collaborations and clinical studies, the preferred applicant will have Oncology expertise. Given the Oncology focus the CP CMP will be a member of the Business Unit Oncology leadership team. They will be asked on occasion to serve as an interim squad lead or Oncology Therapy Aligned CMP (or other TAs dependent on experience) or take on special assignments requiring his or her expertise (e.g ODAC steering committee).

The CP CMP will also coordinate and co-develop the strategy for all the non-Oncology PHC activities including pan-Neurology and pan-Ophthalmology in partnership with the Squads and CMPs. The will in partnership across CMG co-lead a Portfolio CMG Advisory Council that will consider external collaborations.

Execution of Oncology related PHC projects will be done by an Oncology team of Medical Partners directly reporting into the CP CMP. The execution of Non-Oncology related PHC projects by teams not directly reporting into the CP CMP. Decision rights on the strategy for Non-Oncology cross-portfolio PHC sits with the related therapy area CMP.

PHC and cross-portfolio activities are a Roche/Genentech wide company priority. The CP CMP role will be responsible for establishing and partnering across the Roche enterprise on above therapy area (TA) specific initiatives with a focus on Oncology. This will include establishing key partnerships with gRED, pRED, PD, GPS and PDMA. The role will both be focussed on highlighting this critical work internally and enhancing Genentech’s company reputation. The CP CMP is the point of contact with other senior CMG stakeholders including the Commercial BU heads, the Portfolio Marketing Squad Lead. From a PHC perspective they are the point of contact for Global and PDMA PHC Head and partners in other Roche groups including FMI, FIH and Roche DIA.

This individual will assist in the interpretation of and pull through of data with Medical Teams in partnership across the enterprise playing an active role in strategic medical planning and providing oversight of the plans to ensure consistency across the portfolio. The Cross-Portfolio CMP will identify opportunities with impact and prioritize against the portfolio with input from the Business Unit Heads. They are expected to be a coach and strong servant leader across the enterprise to optimize functional excellence, ultimately ensuring an enhanced customer experience.

The Cross-Portfolio Chief Medical Partner (CP CMP) is a core member of Genentech’s Scientific Leadership Team and is responsible for providing deep medical insights and strategic leadership to drive scientific innovation for the company’s therapeutic portfolio focussing on Oncology. This role is pivotal in delivering cross-portfolio prioritization and has end-to-end responsibilities.

It is business critical for Genentech to make all efforts to maintain the highest of compliance standards (a three-star passport rating). This is of Global importance given Genentech’s status as the largest affiliate within the Roche Group.This role will closely partner across the enterprise, specifically with Scientific Operations and the Healthcare Compliance Office, and with Field Medical to clearly communicate the PHC strategy for partnerships .

Given the strategic and high-profile nature of this role, the CMP will also serve as a key medical spokesperson with both internal and external audiences whenever appropriate, including but not limited to the Roche/Genentech Executive Committee, the US Leadership Team, the Roche Group PHC steering committee, and as a JSC member for major PHC collaborations, regulatory bodies, industry forums, and the diverse range of customer and patient organizations.

CORE ACCOUNTABILITIES:

• Translate the corporate strategy of the company into an integrated cross-portfolio clinical strategy in partnership across CMG

• Accountable for successful strategy implementation through cross-portfolio medical tactics, tapping into the network of relevant expertise and insights

• Engage with a variety of internal and external partners and stakeholders, including scientific advisory board and other thought leaders to innovate and refine clinical product development strategies, prioritizing product opportunities and developing plans to generate evidence for clinical validation and clinical utility

• Provide medical expertise on Genentech work products and serve as a clinical resource to cross-functional teams. As a content expert, review medical and commercial documents and publications for promotional or scientific use, ensuring company compliance with regulations

• Establish relationships with thought leaders and key clinicians across the varied segments of interest to ensure Genentech has a clear understanding of customer needs and requirements as well as medical practice patterns

• Collaborate in the design and conduct of clinical studies for product validation including oversight on preparation and review of relevant written documents and oversee the identification and recruitment of principal investigators for studies

• Partner with R&D and Commercial teams to achieve optimal product design specs for diagnostic assays in development and to achieve optimal commercialization of marketed products

• Participate in life cycle management teams to speed the deployment of new products

• Interact with regulatory teams, providing medical / scientific input into regulatory submissions; assist in developing and reviewing all submissions to regulatory authorities, and represent company at key meetings

• Oversee translational efforts with partners and collaborators. Identify and provide guidance on opportunities to jointly promote data in collaboration with research and other strategic partners

• Work in conjunction with Genentech’s Market Access team to shape coverage policies

• Serve as a company spokesperson regarding clinical / medical matters. Lead company resources in addressing clinical and patient product-related inquiries

• Advocate the relevant medical perspective at the Squad level with an enterprise view and a customer-centric approach to drive medical progress

• Inform and collaborate with the medical network to execute on Squad 5-year vision, 90-day priorities, and integrated customer plan

• Partner effectively across USMA internal functions and with global (including PD, PDMA & GPS) colleagues to create and deliver options to support Squad short- and long-term goals

• Lead interactions with regulatory agencies, clinical experts, and work with cross-functional teams to design, develop and implement clinical studies and generate evidence based on customer needs and partner with members of the Squad to develop and communicate an integrated product strategy

• Responsible for enabling a customer centric culture across the medical network, prioritizing customer engagement to share insights, seek input, and identify opportunities to co-create solutions around unmet medical needs

• Serve as a mentor and coach for other Medical Partners and establish an inspiring team culture through continuous demonstration of leadership commitments

• Operate with a P&L mindset at the Squad level

• Act as a guardian for high standards of compliance, ethics and safety

• With the ecosystem leadership team, harness the collective expertise of the ecosystem team to engage effectively and compliantly across the ecosystem. Create and foster a culture that enables and requires employees at all levels to live our Operating Principles in all aspects of their work.

• Act with a P&L mindset to deliver on maximum impact opportunities and apply resources responsibly to achieve our mission.

CMG Operating Principles

• I put the patient first, always.

• I am tenacious in meeting customer needs.

• I act on behalf of the whole company, not just my team.

• I am inclusive.

• I build a culture of trust.

• I grow my capabilities to increase my impact.

• I have a bias for action.

• I am accountable.

• I use time and resources to create the most impact.

• I act with integrity.

QUALIFICATIONS & EXPERIENCES:

• Physician preferred (Board Certified MD or equivalent)

• 10 or more years of pharmaceutical / biotechnology industry experience – preferably in Medical Affairs or Product Development or is a recognized expert in the field. Oncology experience is preferred given the nature of the Cross-Portfolio work.

• Strong academic background is required and drug development experience spanning all phases of research

• Experience leading entire disease area focused teams across different Therapeutic Areas, with an understanding of end-to-end activities of Medical Affairs

• Sophisticated understanding of the evolving regulatory, medical practice and economic environments impacting Roche / Genentech both globally and within the US; have a thorough understanding of US regulatory / FDA requirements

• Demonstrated ability to understand and identify the needs of patients, providers and payers through credible use of health economic outcomes research and / or real-world evidence

• Demonstrated experience in the application of various scientific technologies into translational research strategies

• Substantive understanding and exposure to corporate legal and compliance groups, and be knowledgeable of issues related to, GCP, OIG and other guiding or controlling elements of our business

• A successful track record of collaborating, coaching and influencing outcomes in complex organizations and projects

• Previous people management experience is required with demonstrated ability to mentor and develop emerging leaders

• Strong work ethic with expectation of excellence from self and others. Must have high personal credibility and outstanding written communication skills on scientific topics

• Strong interpersonal and presentation skills, good judgment and ability to communicate with a diverse range of senior stakeholders

• Strong understanding and connectivity to regional ecosystems teams is highly preferred to ensure medical strategies address unmet medical needs within ecosystem

• Responsible for representing Genentech at key executive exchanges and fostering relationships with top tier thoughts leaders in specific disease area of expertise

• Scientific credibility and enterprise thinking on how medical affairs impacts the broader organization and ability to provide proactive solutions to complex enterprise needs

• Finance and / or large-scale budget development, management and administration experience

• Understanding and familiarity with agile ways of working

• Knowledge and experience in digital and analytics

• Business travel, by air or car, is required for regular internal and external business meetings

• Complies with all laws, regulations, policies and procedures that govern the conduct of GNE activities